How effective is Provigil in treating Alzheimer’s Disease?

provigil for alzheimerProvigil (Modafinil) is the primary FDA-affirmed prescription drug for treatment of excessive sleepiness connected with Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) and Shift worker Sleep Disorder (SWSD). Provigil was affirmed by the FDA in 1998 for the treatment of excessive daytime sleepiness connected with narcolepsy but at the same time is utilized by numerous for “off-label” conditions.

These incorporate age-related memory decrease, a lack of ability to concentrate consistently scatter, depression, weakness from high-pressure employments, chemotherapy and numerous sclerosis, and for memory issues connected with Alzheimer’s disease, post-anesthesia tiredness, sleepiness brought about by other prescription medications and as a treatment for a cocaine habit. Further, purchasing Provigil medication from reputed and authentic Canadian drugstores improves attentiveness, concentration and carefulness, however, its pharmacological profile is prominently not the same as the amphetamines, methylphenidate (Ritalin) or cocaine.

Provigil is less inclined to bring about nervousness, uneasiness, or uncontrolled motor coordination – or lead to a hyper somnolent ‘rebound impact’ – than customary stimulants. Subjectively, Provigil feels smoother and cleaner than the amphetamines as well. It might even be anxiolytic, however reports differ. The typical end half-existence of Modafinil in people is between 12 – 15 hours. So it’s worth calibrating one’s dose schedule in a similar manner. Executive capacity might be improved by its continued dosage but not creativity or compassion. Tentatively, Provigil is likewise utilized as a part of the treatment of Alzheimer’s malady.

How does the Provigil drug work?

The instruments of activity for Provigil medication are obscure. Some portion of its impact is thought to be intervened by orexins and neuropeptides that advance alertness. Stimulation of orexinergic neurons has been appeared to expand the centralization of amyloid-beta in the mind and the collection of amyloid-beta is focusing subordinate.

Amyloid-beta total is embroiled in the improvement of Alzheimer’s sickness, thus questioning the intelligence of taking Provigil and misleadingly quickening the pathways involved in this procedure. Moreover, Modafinil may expand your danger for Alzheimer’s sickness which is the primary concern. The system is conceivable keeping in mind there are no continued research studies to bolster this idea. However, there are several experts who support this idea and refuse to prescribe Provigil for treating Alzheimer’s.

Why is it not encouraged to treat Alzheimer with Provigil?

There is no proof that a person with Alzheimer can get benefitted by taking Provigil medication. Another important factor is that the FDA has not approved this drug for the medical ailment. Though it is widely recommended to take other medications that are available in the market to treat Alzheimer, there are some instances at which a doctor might suggest these patients take Provigil.

When a healthcare professional finds that this medication can provide you with great effectiveness then they would encourage Alzheimer patients to take Provigil. They would be in a position to legally provide a prescription in this case. You have to know that, only as a last resort a medico would instruct people to take Provigil to treat Alzheimer.

This is also because we are less aware of the side effects that are triggered in a person while he or she is taking the Provigil pills for Alzheimer. Few patients would be benefitted by this medication whereas others would have no effect on them.

However, only when this wakefulness promoting agent is taken by a person, one would be able to find out whether it is worth taking or not.